Docente

Página Web de GLORIA MORCILLO ORTEGA

Dra. Gloria Morcillo Ortega
Grupo de Biología y Toxicología Ambiental
Departamento de Física Matemática y de Fluidos
Facultad de Ciencias – UNED

Paseo de la Senda del Rey 9
Madrid 28040
Tfno: +34 91 398 7328

PROYECTOS DE INVESTIGACIÓN

• Ecotoxicología de disruptores endocrinos en invertebrados acuáticos: efectos genéticos y epigenéticos. Ministerio de Economía y Competitividad. Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica. CTM2012-37547 (2013-2016). IP: G. MORCILLO
• Evaluación del impacto de disruptores endocrinos ambientales en invertebrados bénticos. Identificación de biomarcadores moleculares por medio de tecnologías genómicas en Chironomus riparius como especie modelo en toxicología acuática. Ministerio de Ciencia e Innovación. Plan Nacional de I+D. CTM2009-07189 (2010-2012). IP: G. MORCILLO
• Caracterización de biomarcadores de ecotoxicidad acuática en el organismo de referencia Chironomus riparius frente a metales y compuestos orgánicos disruptores endocrinos. Ministerio de Educación y Ciencia. Plan Nacional de I+D. CTM2006-12479/TECNO (2006-2009). IP: G. MORCILLO

PUBLICACIONES (últimos 5 años)

• Planelló R, Servia M J, Gómez-Sande P, Herrero O, Cobo F, Morcillo G. (2013). Evaluating multi-biomarker responses in laboratory and natural populations of the aquatic midge Chironomus riparius sampled in three polluted rivers in Galicia (Spain). (acepted) doi: 10.1002/tox.21893.
• Morales M. Martínez-Paz, P, Ozáez I, Martínez-Guitarte JL, Morcillo G. (2013). DNA damage and transcriptional changes induced by Tributyltin (TBT) after short in vivo exposures of Chironomus riparius (Diptera) larvae. Comparative Biochemistry and Physiology, Part C (acepted) 

  http://dx.doi.org/10.1016/j.cbpc.2013.05.005

• Ozáez I, Martínez-Guitarte JL, Morcillo G. (2013). Effects of in vivo exposure to UV filters (4-MBC, OMC, BP-3, 4-HB, OC, OD-PABA) on endocrine signaling genes in the insect Chironomus riparius. Science of the Total Environment 456-457, 120-126.  
• Martínez-Guitarte JL, Planelló R, Morcillo G. (2012). Overexpression of long non-coding RNAs following exposure to xenobiotics in the aquatic midge Chironomus riparius. Aquatic Toxicology 110-111, 84-90.
• Martínez-Paz P, Morales M, Martínez-Guitarte JL, Morcillo G. (2012). Characterization of a cytochrome P450 gene (CYP4G) and modulation under different exposures to xenobiotics (tributyltin, nonylphenol, bisphenol A) in Chironomus riparius aquatic larvae. Comparative Biochemistry and Physiology, Part C, 155, 333-343.
• Planelló R, Herrero O, Martínez-Guitarte JL, Morcillo G. (2011). Comparative effects of butyl benzyl phthalate (BBP) and di(2-ethylhexyl) phthalate (DEHP) on the aquatic larvae of Chironomus riparius based on gene expression assays related to the endocrine system, the stress response and ribosomes. Aquatic Toxicology 105, 62-70.
• Morales M, Planelló R, Martínez-Paz P, Herrero O, Cortés E, Martínez-Guitarte JL, Morcillo G. (2010). Characterization of Hsp70 gene in Chironomus riparius: expression in response to endocrine disrupting pollutants as a marker of ecotoxicological stress. Comparative Biochemistry and Physiology, Part C, 150, 150 – 158.
• Martinez-Paz P, Morales M, Martínez-Guitarte JL. Morcillo G. (2010). Evaluation of the effects of nonylphenol on fourth-instar larvae of Chironomus riparius (Diptera). Comparative Biochemistry and Physiology 57A, S25.
• Planelló R, Martínez-Guitarte JL, Morcillo G. (2010). Environmental pollutans and non-coding telomeric RNA levels in Chironomus riparius. Comparative Biochemistry and Physiolog 157A, 56.
• Planelló R, Martínez-Guitarte JL, Morcillo G. (2010). Effect of acute exposure to cadmium on the expression of heat-shock and hormone-nuclear receptor genes in the aquatic midge Chironomus riparius. Science of the Total Environment 408, 1598-1603.
• Morcillo G, Planelló R, Morales M, Cortés E, de Paz PM, Martínez-Guitarte JL. (2009). Identification of molecular biomarkers for endocrine disrupting compounds in Chironomus riparius (Diptera), a model species in aquatic toxicology. Toxicology Letters 189S, 194.
• Martínez-Guitarte JL, Planelló R, Morcillo G. (2009) .Modulation of telomeric RNA expression by Bisphenol A and Cadmium in Chironomus riparius (Diptera). Comparative Biochemistry and Phisiology 154A, S18.
• Planelló R, Martínez-Guitarte JL, Morcillo G. (2009). Ecdysone receptor as a biomarker of cadmium chloride toxicity in the aquatic larvae of Chironomus riparius. Science of the Total Environment 408, 1598-1603.
• Díez JL, Martínez-Guitarte JL, Gorab E, Morcillo G. (2009). Transcriptional activity at the telomeres of Chironomus (Diptera). Its possible role in the lengthening of telomeres. In: Telomeres: Function, shortening and lengthening. Ed. Leonardo Mancini. NOVA Publishers, NY.
• Martínez-Guitarte JL, Díez JL, Morcillo G. (2008). Changes in the ecdysone response pathway after exposure to cadmium, pentachlorophenol and bisphenol A in the aquatic larvae of Chironomus. Toxicology Letters 180S, 190-191.
• Planelló R, Martínez-Guitarte JL, Morcillo G. (2008). Effect of bisphenol-A in the expression of housekeeping, stress-induced and hormone-related genes in the aquatic larvae of the midge Chironomus. Toxicology Letters 180S, 197.
• Martínez-Guitarte JL, Planelló R, Morcillo G. (2008). Changes in the ecdysone response pathway after exposure to different endocrine-disrupting chemicals in the aquatic larvae of Chironomus riparius. Comparative Biochemistry and Physiology 151A, 56-57.
• Martínez-Guitarte JL, Díez JL, Morcillo G. (2008). Transcription and activation under environmental stress of the complex telomeric repeats of Chironomus thummi. Chromosome Research 16, 1085-1096.
• Planelló R, Martínez-Guitarte JL, Morcillo G. (2008). The endocrine disruptor bisphenol A increases the expression of HSP70 and ecdysone-receptor genes in the aquatic larvae of Chironomus riparius. Chemosphere 71, 1870-1876.
• Planelló R, Martínez-Guitarte JL, Morcillo G. (2007). Efectos de la exposición a bisfenol A en larvas acuáticas de Chironomus riparius. Revista de Toxicología vol 24, 81.
• Martínez-Guitarte JL, Planelló R, Morcillo G. (2007). Caracterización del efecto a nivel celular de la exposición a diversos compuestos con actividad disruptora endocrina en larvas acuáticas de Chironomus riparius. Revista de Toxicología vol 24, 80.
• Martínez-Guitarte JL, Planelló R, Morcillo G. (2007). Characterization and expression during development and under environmental stress of the genes encoding ribosomal proteins L11 and L13 in Chironomus riparius. Comparative Biochemistry and Physiology 147, 509-596.
• Planelló R, Martínez-Guitarte JL, Morcillo G. (2007). Ribosomal genes as early targets of cadmium- induced toxicity in Chironomus riparius larvae. Science of the Total Environment 373, 113-121.